Purified CBD can lead the full remission of seizures in those with epilepsy.
The study, which was published online by the National Institute of Health, is titled “Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol”.
According to the study’s abstract; “Animal studies and preliminary clinical trials have shown that cannabidiol (CBD)-enriched extracts may have beneficial effects for children with treatment-resistant epilepsy.” However, these compounds “are not yet registered as medicines by regulatory agencies.”
For the study, researchers “describe the cases of two children with treatment-resistant epilepsy (Case A with left frontal dysplasia and Case B with Dravet Syndrome) with initial symptom improvement after the introduction of CBD extracts followed by seizure worsening after a short time.”
The children presented typical signs of intoxication by Δ9-THC, which researchers refereed to as “inappropriate laughter, ataxia, reduced attention, and eye redness”, after using a CBD-enriched extract. The extract was replaced by the same dose of purified CBD with no Δ9-THC in both cases, which “led to improvement in intoxication signs and seizure remission.”
“The study concludes; “These cases support pre-clinical and preliminary clinical evidence suggesting that CBD may be effective for some patients with epilepsy. Moreover, the cases highlight the need for randomized clinical trials using high-quality and reliable substances to ascertain the safety and efficacy of cannabinoids as medicines.”
The full study can be viewed by clicking here.