According to a new study published in the journal Frontiers in Pharmacology, purified CBD can lead the full remission of seizures in those with epilepsy.
The study, which was published online by the National Institute of Health, is titled "Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol".
According to the study's abstract; "Animal studies and preliminary clinical trials have shown that cannabidiol (CBD)-enriched extracts may have beneficial effects for children with treatment-resistant epilepsy." However, these compounds "are not yet registered as medicines by regulatory agencies."
For the study, researchers "describe the cases of two children with treatment-resistant epilepsy (Case A with left frontal dysplasia and Case B with Dravet Syndrome) with initial symptom improvement after the introduction of CBD extracts followed by seizure worsening after a short time."
The children presented typical signs of intoxication by Δ9-THC, which researchers refereed to as "inappropriate laughter, ataxia, reduced attention, and eye redness", after using a CBD-enriched extract. The extract was replaced by the same dose of purified CBD with no Δ9-THC in both cases, which "led to improvement in intoxication signs and seizure remission."
"The study concludes; "These cases support pre-clinical and preliminary clinical evidence suggesting that CBD may be effective for some patients with epilepsy. Moreover, the cases highlight the need for randomized clinical trials using high-quality and reliable substances to ascertain the safety and efficacy of cannabinoids as medicines."
The full study can be viewed by clicking here.